ABSTRACT Globally, an estimated 3.4 billion people are at risk of malaria, including Nigerians. The current World Health Organization (WHO) Guideline for the treatment of malaria recommends the use of artemisinin combination therapy (ACT) for the treatment of uncomplicated malaria. Presently, the available formulations of ACTs are administered... Continue Reading
Piliostigma reticulatum plant found in West Africa. It is an Evergreen shrub with a twisted bole to 9 m high, with a bushy spherical canopy. Bark dark grey to brown, fibrous and corky, slash dark red. Leaves large, thick, leathery, grey-green, 6-12 cm long, Fruit large, long, straight, undulate or twisted and hard, either glabrous or sparsely... Continue Reading
ABSTRACT Despite the reported rapid increase in demand for artemisinin and its derivatives, there is little independent collaboration of the toxicity patterns of artemether-lumefantrine combination besides those documented by the manufacturer in its application for approval. It is however, pertinent to conduct an independent evaluation of the... Continue Reading
Spondias mombin is depends on for various herbal remedies for the treatment of numerous health conditions. This study is to evaluate the In-vivo toxic effect of Stem bark extracts of Spondias mombin on in male and female albino rats. In-vivo toxicity test was carried out with modified Lorke’s method. Forty two (42) male and female albino... Continue Reading
ABSTRACT The study was aimed at evaluating the antidiabetic potentials of Anogeissius leiocarpus DC Guill and Perr root bark methanol, ethanol and ethanol plus trona extract; and preparing, characterizing and evaluating lipospheres as drug delivery system loaded with A.leiocarpus root bark methanol extract. 400 mg/kg of methanol,ethanol and... Continue Reading
TABLE OF CONTENTS CONTENTS PAGE TITLE PAGE---------i DECLARATION--------ii CERTIFICATION--------iii DEDICATION--------iv ACKNOWLEDGEMENT-------v TABLE OF CONTENT-------vi LIST OF TABLES--------ix LIST OF FIGURES-------ix ABSTRACT---------x CHAPTER ONE INTRODUCTION AND LITERATURE REVIEW 1.1 TRADITIONAL MEDICINE-------1 1.2 MODERN MEDICINE--------4... Continue Reading
The field of nano science plays a crucial role in modern research and technology, offering unparalleled opportunities for innovation. Spondias mombin extract is used in this study as a bioreducing agent for the biosynthesis of silver nanoparticles (AgNPs). The properties of these nanoparticles are compared. As the color of the extract changed from... Continue Reading
PROPOSAL: ABSTRACT Background: Currently stroke represents a serious problem in public health as one of the leading causes of mortality and morbidity worldwide [1-3] with developing countries accounting for 85% of global deaths from stroke [1, 3-5]. A very good example explains how stroke seems to be increasing in Nigeria and the case fatality... Continue Reading
ABSTRACT The usefulness of non-steroidal anti-inflammatory agents in the management of rheumatoid diseases cannot be over-emphasized. As this disease is characterized by chronic inflammation, it is usual to test compounds for anti-inflammatory activity in animals and then hope that the active ones should be clinically useful as anti-rheumatic... Continue Reading
ABSTRACT Fatty seed extracts of Vitellaria paradoxa (Sapotaceae), an indigenous plant of West Africa is a popular remedy for arthritis and swellings. This study investigated the knowledge, prevalence and pattern of use of the fatty extract also known as shea butter in clinically diagnosed arthritic patients as well as its effects on acute... Continue Reading
The use of herbal medicines, despite the advancement in production of orthodox ones, has been on the increase, both in underdeveloped, developed and developing countries like Nigeria in particular. The approval of these herbal remedies by regulatory bodies like the National Agency for Food and Drug Administration Control, (NAFDAC) in Nigeria has... Continue Reading
ABSTRACT Globally, an estimated 3.4 billion people are at risk of malaria, including Nigerians. The current World Health Organization (WHO) Guideline for the treatment of malaria recommends the use of artemisinin combination therapy (ACT) for the treatment of uncomplicated malaria. Presently, the available formulations of ACTs are administered... Continue Reading