Most Relevant Pharmaceutical Science Project Topics and Materials

Showing 1 - 25 of 87

1) USE OF CARICA PAPAYA SEEDS IN A SUSPENSION FOR THE TREATMENT OF INTESTINAL PARASITIC WORMS

ABSTRACT The seeds of a tropical fruit Carica papaya have been proven to have anthelminthic activity. The main component in the seeds responsible for this activity is Benzyl isothiocyanate. It is effective against parasites such Ascaris lumbricoides, Strongyloides stercoralis, Taenia saginata and so on. The research focus on formulating an... Continue Reading

2) THE USE OF QUALITY CONTROL PARAMETERS IN THE EVALUATION OF VEGETABLE CRUDE DRUGS

CHAPTER ONE INTRODUCTION  BACKGROUND OF THE STUDY The universal role of plants in the treatment of disease is exemplified by their employment in all the major systems of medicine irrespective of the underlying philosophical premise. How and when such medicinal plants... Continue Reading

3) PROFILE OF ANTIBIOTIC USE AT THE HEALTH CENTRE

Abstract The indiscriminate use of antibiotics has become a global problem with implications for effective therapy of infections and dose resistance. The objective of this study is to determine the profile of antibiotic use at the health centre of Delta State University, Abraka. This study was a retrospective study of 592 patient prescriptions... Continue Reading

4) ASSESSMENT OF HEALTH WORKERS' ADHERENCE TO STANDARD TREATMENT GUIDELINES IN MANAGEMENT OF TYPHOID FEVER AT KAMPALA INTERNATIONAL UNIVERSITY TEACHING HOSPITAL.

TABLE OF CONTENTS DECLARATION ............................................................................................................................. .i CERTIFICATION .......................................................................................................................... ii LIST OF ABREVIATIONS... Continue Reading

5) ANTIMICROBIAL, PHYTOCHEMICAL AND PROXIMATE ANALYSIS OF FOUR NIGERIAN MEDICINAL PLANTS ON SOME CLINICAL MICROORGANISMS

The increasing incidence of resistance to antibiotics among bacteria currently poses serious clinical and public health threat and has propelled efforts for newer alternatives to alleviate the problem. Extensive search and testing for different plants with potentials for antimicrobial properties is presently considered one of the most feasible... Continue Reading

6) THE EFFECT OF PHARMACISTS' MONITORING ROLE ON CLINICAL OUTCOMES OF HYPERTENSIVE PATIENTS ATTENDING TWO TERTIARY REFERRAL HOSPITALS

TABLE OF CONTENTS DECLARATION .................................................................................................................................. i CERTIFICATION ............................................................................................................................... ii DEDICATION... Continue Reading

7) ANTI MICROBIAL AND PHYTOCHEMICAL STUDIES ON SELECTED NIGERIAN MEDICINAL PLANTS: (1) ANTI MICROBIAL AND PHYTOCHEMICAL PROPERTIES OF PHYLLANTHUS DISCOIDEUS (EUPHORBIACEAE).

ABSTRACT The aqueous methanolic extracts of 20 selected plant parts were screened for in-vitro antimicrobial activity against clinical strains of Staphylococcus aureus, Bacillus subtilis, Klebsiella pneumonia, Salmonella typhi, Escherichia coli, Pseudomonas aeruginosa, Aspergillus niger and Candida albicans at a test concentration of 10mg/ml using... Continue Reading

8) THE CAUSES AND EFFECTS OF CHOLERA AMONG CHILDREN

ABSTRACT This research work was designed to examine and analyze the causes and effects of cholera during raining season in Benin City. Seven (7) research questions were formulated and questionnaires were administered to one hundred and fifty (150) respondents in order to gather data for the research. Results showed that poor environment sanitation... Continue Reading

9) DEVELOPMENT OF LIPID-BASED MICRO SUSPENSIONS FOR OPHTHALMIC DELIVERY OF GENTAAMICIN

ABSTRACT The bioavailability of drugs from conventional eye drops is generally low. Many studies have demonstrated that new and more complex ophthalmic drug forms exhibit advantage over traditional ones and are able to increase the bioavailability of the active substance by, among others, reducing the susceptibility of drug forms to defense... Continue Reading

10) THE ANXIOLYTIC ACTIVITY OF ETHANOLIC LEAF EXTRACT OF CULCASIAN SCADENS IN EXPERIMENTAL ANIMAL MODELS

ABSTRACT Objectives: to explore the anxiolytic activity of ethanolic leaf extract of culcasian scadens in experimental animal models . Methods:  The anxiolytic activity was examined by using the elevated plus maze (EPM) and open field test (OFT), hole board test and light and dark box exploration test. Twenty Swiss albino male mice were divided... Continue Reading

11) PHYTOCHEMICAL AND PROXIMATE

The purpose of this present study of seven Nigerian medicinal plants is to ascertain the medicinal, phytochemical and proximate constituents of the plants. The plants are .Acacia albida Del,   Anchomanes difformis Engl,   Boscia senegalensis,   Bridelia ferruginea Benth,  Ficus ingens (Miq.) Miq,  Indigofera arrecta   Hochst   and ... Continue Reading

12) COMPARATIVE STUDY OF THE ANTIBACTERIAL AND ANTIFUNGAL SPECTRUM, PHYTOCHEMI

 Piliostigma reticulatum plant found in West Africa. It is an Evergreen shrub with a twisted bole to 9 m high, with a bushy spherical canopy. Bark dark grey to brown, fibrous and corky, slash dark red. Leaves large, thick, leathery, grey-green, 6-12 cm long, Fruit large, long, straight, undulate or twisted and hard, either glabrous or sparsely... Continue Reading

13) ANTIMICROBIAL ACTIVITY AND PHYTOCHEMICAL COMPOSITION OF CRUDE ETHYL ACETATE EXTRACTS OF ANISOPUS MANNI

 Anisopus mannii(Asclepiadaceae) –is a glabrous twining shrub, strong climber with greenish flower in globose, lateral umbelliform cymes it is widely used as an anti-diabetic agent in Northern and southern Nigerian traditional medicine, Studies were conducted to determine the phytochemical constituents of leaf and bark ethyl acetate extracts of... Continue Reading

14) ANTIBACTERIAL SENSITIVITY PROFILE, ISOLATION AND IDENTIFICATI ON OF BACTERIA USING API 20E KITS

The purpose of this research work is to determine the microbiological profile of hospital solid waste dump sites, sensitivity to antibiotic and isolation and identification of the organism using API 20 E kit method of analysis. Microbiological profiling was carried out on hospital solid waste collected from State Specialist Hospital in... Continue Reading

15) ASSESSMENT OF ANTIMICROBIAL AND PHYTOCHEMICAL PROPERTIES OF CRUDE LEAF AND BARK EXTRACTS OF CEIBA PENTANDRA ON SELECTED CLINICAL ISOLATES FOUND IN NIGERIAN TEACHING HOSPITAL

Abstract Ceiba pentandra is a tropical tree of order Malvales and the family Malvaceae. The basic objective of this research work is to determine the antimicrobial and phytochemical properties of Ceiba pentandra. Fresh leaves and bark of Ceiba petandra was collected at Akungba Akoko. Ceiba pentandra (leaf and bark) were prepared for extraction... Continue Reading

16) EFFECT OF AQEUOUS EXTRACT OF RAUWOLA VOMITORIA ROOT EXTRACT ON ISOLATED RABBIT INTESTINE

Rauwolfia vomitoria is a natural medicinal herb which has been used over the years for the treatment of hypertension and mental disorders. This is to investigate the inhibitory effect of RAUWOLFIA VOMITORIA aqueous root extract on invitro isolated rabbit intestine precontracted with Acetylcholine. The effect of the root extract was compared with... Continue Reading

17) TOXICITY ASSESSMENT OF STEM BARK EXTRACTS

Spondias mombin is depends on for various herbal remedies for the treatment of numerous health conditions. This study  is to evaluate the In-vivo toxic effect of Stem bark extracts of Spondias mombin on in male and female albino rats. In-vivo   toxicity test was carried out with modified Lorke’s method. Forty two (42) male and female albino... Continue Reading

18) NEUTRALIZATION OF THE LETHAL EFFECT OF BITIS ARIETANS VENOMBY EUPHORBIA COTINIFOLIA LEAF EXTRACT

TABLE OF CONTENTS CONTENTS PAGE TITLE PAGE - - - - - - - - - i DECLARATION - - - - - - - - ii CERTIFICATION - - - - - - - - iii DEDICATION - - - - - - - - iv ACKNOWLEDGEMENT - - - - - - - v TABLE OF CONTENT - - - - - - - vi LIST OF TABLES - - - - - - - - ix LIST OF FIGURES - - - - - - - ix ABSTRACT - - - - - - - - - x CHAPTER ONE INTRODUCTION AND... Continue Reading

19) EFFECT OF COMBINED TREATMENT WITH CHLOROQUINE AND ARTESUNATE ON WHITE BLOOD CELL COUNT OF PLASOMDIUM BERGHEI INFECTED ALBINO MICE

ABSTRACT Malaria is an enormous public health problem worldwide and kills one to two million people every year, mostly children residing in Africa . And the aim of this study is to determine the impact of combined treatment with Artesunate and Chloroquine on the white blood cell count of plasmodium berghei infected albino mice. And to compare and... Continue Reading

20) ANTI-ULCEROGENIC EFFECTS OF CHLOROFORM EXTRACT OF CHASMANTHERA DEPENDENS ON INDOMETHACIN AND ASPIRIN-IDUCED ULCER IN RATS

Peptic ulcer is one of the leading causes of gastrointestinal surgery with high morbidity and mortal￾ity rates. This study assessed the anti-ulcerogenic effect of the chloroform extract of Chasmanthera dependens on indomethacin and aspirin-induced ulcer in rats. Fifty (50) adult rats were divided into two broad groups of twenty five rats each... Continue Reading

21) EFFECT OF ETHANOLIC LEAF EXTRACT OF DIALIUM GUINEENSE WILD. (FABACEAE) ON ORAL GLUCOSE TOLERANCE IN MICE AND ALLOXAN-INDUCED DIABETIC FEMALE RATS

This research project studied the effect of ethanolic leaf extract of Dialium guineense Willd (Fabaceae) on oral glucose tolerance in mice and alloxan-induced diabetic female rats.  The ethanolic leaf extract was prepared by marcerating 500g of the dried, milled leaves of D. guineense in 3L of 96% ethanol in a suitable sized plastic bucket/bowl... Continue Reading
  • Type:Project
  • ID:PHS0019
  • Pages:105

22) PROTECTIVE ROLE OF AQUEOUS LEAF EXTRACT OF VERNONIA AMYGDALINA DEL. (ASTERACEAE) AND OCIMUM GRATISSIMUM LINN (LAMIACEAE) IN CYCLOPHOSPHAMIDE INDUCED UROTOXICITY AND MYELOSUPPRESSION

ABSTRACT Cyclophosphamide (CP) is one of the most potent and widely used alkylating anticancer agents. Urotoxicity and myelosuppression is known as the most prevailing dose-limiting toxicity associated with CP. In the present study, the protective potential of Vernonia amygdalina and Ocimum gratissimum aqueous leaf extracts in CP-induced... Continue Reading
  • Type:Project
  • ID:PHS0020
  • Pages:112

23) ANTIDIABETIC POTENTIALS OF LIPOSPHERES ENCAPSULATING ANOGEISSUS LEIOCARPUS DC GUILL & PERR ROOT BARK METHANOL EXTRACT

ABSTRACT The study was aimed at evaluating the antidiabetic potentials of Anogeissius leiocarpus DC Guill and Perr root bark methanol, ethanol and ethanol plus trona extract; and preparing, characterizing and evaluating lipospheres as drug delivery system loaded with A.leiocarpus root bark methanol extract. 400 mg/kg of methanol,ethanol and... Continue Reading
  • Type:Project
  • ID:PHS0021
  • Pages:114

24) PREDICTING INTESTINAL PERMEATION OF DRUGS THROUGH NEURAL NETWORK ANALYSIS BASED ON FIVE MOLECULAR DESCRIPTORS

ABSTRACT The oral route is generally preferred for drug administration because of its ease and good patient compliance. In the search for new drugs for oral administration a major problem encountered is obtaining drug structures which, as well as being potent in viiro, possess favourable pharmacokinetic profiles which enable them to pass easily... Continue Reading
  • Type:Project
  • ID:PHS0022
  • Pages:137

25) STUDIES ON THE IN VITRO AND IN VIVO INTERACTION OF COLD WATER EXTRACT OF AZADIRACHTA INDICA (NEEM) LEAVES WITH SOME ANTIBIOTICS

ABSTRACT T he present study investigated herb-drug interactions involving cold water extract of Azadirachta indica (neem) leaves, with five classes of antibiotics, namely: Tetracyclines - Tetracycline (TET) and Doxycycline POX); I Penicillins - Penicillin G(PG) and Ampicillin (AMP); Cephalosporins - Cefuroxime (CF); Arninoglycosides -Gentamicycin... Continue Reading
  • Type:Project
  • ID:PHS0023
  • Pages:118
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