Pharmaceutical Science Project Topics and Materials

ABSTRACT The bioavailability of drugs from conventional eye drops is generally low. Many studies have demonstrated that new and more complex ophthalmic drug forms exhibit advantage over traditional ones and are able to increase the bioavailability of the active substance by, among others, reducing the susceptibility of drug forms to defense... Continue Reading

ABSTRACT This research work was designed to examine and analyze the causes and effects of cholera during raining season in Benin City. Seven (7) research questions were formulated and questionnaires were administered to one hundred and fifty (150) respondents in order to gather data for the research. Results showed that poor environment sanitation... Continue Reading

Abstract The indiscriminate use of antibiotics has become a global problem with implications for effective therapy of infections and dose resistance. The objective of this study is to determine the profile of antibiotic use at the health centre of Delta State University, Abraka. This study was a retrospective study of 592 patient prescriptions... Continue Reading

This research project studied the effect of ethanolic leaf extract of Dialium guineense Willd (Fabaceae) on oral glucose tolerance in mice and alloxan-induced diabetic female rats.  The ethanolic leaf extract was prepared by marcerating 500g of the dried, milled leaves of D. guineense in 3L of 96% ethanol in a suitable sized plastic bucket/bowl... Continue Reading

ABSTRACT Malaria is an enormous public health problem worldwide and kills one to two million people every year, mostly children residing in Africa . And the aim of this study is to determine the impact of combined treatment with Artesunate and Chloroquine on the white blood cell count of plasmodium berghei infected albino mice. And to compare and... Continue Reading

Peptic ulcer is one of the leading causes of gastrointestinal surgery with high morbidity and mortal￾ity rates. This study assessed the anti-ulcerogenic effect of the chloroform extract of Chasmanthera dependens on indomethacin and aspirin-induced ulcer in rats. Fifty (50) adult rats were divided into two broad groups of twenty five rats each... Continue Reading

TABLE OF CONTENTS CONTENTS PAGE TITLE PAGE - - - - - - - - - i DECLARATION - - - - - - - - ii CERTIFICATION - - - - - - - - iii DEDICATION - - - - - - - - iv ACKNOWLEDGEMENT - - - - - - - v TABLE OF CONTENT - - - - - - - vi LIST OF TABLES - - - - - - - - ix LIST OF FIGURES - - - - - - - ix ABSTRACT - - - - - - - - - x CHAPTER ONE INTRODUCTION AND... Continue Reading

Rauwolfia vomitoria is a natural medicinal herb which has been used over the years for the treatment of hypertension and mental disorders. This is to investigate the inhibitory effect of RAUWOLFIA VOMITORIA aqueous root extract on invitro isolated rabbit intestine precontracted with Acetylcholine. The effect of the root extract was compared with... Continue Reading

Spondias mombin is depends on for various herbal remedies for the treatment of numerous health conditions. This study  is to evaluate the In-vivo toxic effect of Stem bark extracts of Spondias mombin on in male and female albino rats. In-vivo   toxicity test was carried out with modified Lorke’s method. Forty two (42) male and female albino... Continue Reading

ABSTRACT The seeds of a tropical fruit Carica papaya have been proven to have anthelminthic activity. The main component in the seeds responsible for this activity is Benzyl isothiocyanate. It is effective against parasites such Ascaris lumbricoides, Strongyloides stercoralis, Taenia saginata and so on. The research focus on formulating an... Continue Reading

Abstract Ceiba pentandra is a tropical tree of order Malvales and the family Malvaceae. The basic objective of this research work is to determine the antimicrobial and phytochemical properties of Ceiba pentandra. Fresh leaves and bark of Ceiba petandra was collected at Akungba Akoko. Ceiba pentandra (leaf and bark) were prepared for extraction... Continue Reading

The increasing incidence of resistance to antibiotics among bacteria currently poses serious clinical and public health threat and has propelled efforts for newer alternatives to alleviate the problem. Extensive search and testing for different plants with potentials for antimicrobial properties is presently considered one of the most feasible... Continue Reading

The purpose of this present study of seven Nigerian medicinal plants is to ascertain the medicinal, phytochemical and proximate constituents of the plants. The plants are .Acacia albida Del,   Anchomanes difformis Engl,   Boscia senegalensis,   Bridelia ferruginea Benth,  Ficus ingens (Miq.) Miq,  Indigofera arrecta   Hochst   and ... Continue Reading

 Piliostigma reticulatum plant found in West Africa. It is an Evergreen shrub with a twisted bole to 9 m high, with a bushy spherical canopy. Bark dark grey to brown, fibrous and corky, slash dark red. Leaves large, thick, leathery, grey-green, 6-12 cm long, Fruit large, long, straight, undulate or twisted and hard, either glabrous or sparsely... Continue Reading

 Anisopus mannii(Asclepiadaceae) –is a glabrous twining shrub, strong climber with greenish flower in globose, lateral umbelliform cymes it is widely used as an anti-diabetic agent in Northern and southern Nigerian traditional medicine, Studies were conducted to determine the phytochemical constituents of leaf and bark ethyl acetate extracts of... Continue Reading

The purpose of this research work is to determine the microbiological profile of hospital solid waste dump sites, sensitivity to antibiotic and isolation and identification of the organism using API 20 E kit method of analysis. Microbiological profiling was carried out on hospital solid waste collected from State Specialist Hospital in... Continue Reading

ABSTRACT Objectives: to explore the anxiolytic activity of ethanolic leaf extract of culcasian scadens in experimental animal models . Methods:  The anxiolytic activity was examined by using the elevated plus maze (EPM) and open field test (OFT), hole board test and light and dark box exploration test. Twenty Swiss albino male mice were divided... Continue Reading

CHAPTER ONE INTRODUCTION  BACKGROUND OF THE STUDY The universal role of plants in the treatment of disease is exemplified by their employment in all the major systems of medicine irrespective of the underlying philosophical premise. How and when such medicinal plants... Continue Reading