Recent Bio-Chemistry Project Topics and Materials (Page 7)

Activation of caspase 3&9 by methanol extract of Gloriosa superba  ABSTRACT Mitochondrion is the key regulator in cellular energy homeostasis and plays a central role in determining cell apoptotic process; it is therefore regarded as a vital target for cancer chemotherapy.   Cancer is obviously one of the most common areas where demand for... Continue Reading

ABSTRACT  Evidences have implicated free radicals or reactive oxygen species in mercuric chloride-induced nephrotoxicity. Diphenyl diselenide (PhSe)2, a simple and stable organoselenium compound, has been proposed as a good candidate for pharmacological and therapeutic purposes. This particular study was designed to investigate the protective... Continue Reading

ABSTRACT Several plants have been used in the treatment of various disorders without scientific basis. The present study examine the pancreatic effect of Buchholzia coriacea formulated diet in sucrose-fed pregnant rats and their offspring. Buchholzia coriacea seeds were obtained from Ogbete main market, Enugu state, identified, dried and grounded... Continue Reading

ABSTRACT Consumption of green tea ( Camellia sinensis ) may provide protection against chronic diseases, including cancer. Green tea polyphenols are believed to be responsible for this cancer preventive effect, and the antioxidant activity of the green tea polyphenols has been implicated as a potential mechanism. This hypothesis has been difficult... Continue Reading

ABSTRACT Vegetables has been an integral part of day to day diet for so many people in Kenya. It is used in the form of raw fruits, dried, powdered or cooked vegetables. This is a research that addresses this way of living to act as a precaution towards making the food healthier. It is with a significantconcentration in Kenyatta market than... Continue Reading

ABSTRACT Coconut water is a natural nutritious beverage that contains several biologically active compounds. This study was set up to evaluate the antioxidant potential of coconut water. Twenty five adult male albino rats, used in this work, were grouped into five (A, B, C, D and E), of five rats per group. Groups A, B, C and D were administered... Continue Reading

The overall objective of this study is to scientifically evaluate the claimed fertility enhancing potential and to assess the metabolic effect of the ethanolic extract of Sphenocentrum jollyanum pierre (Menispermaceae) root using male wistar rats as model. The specific objectives include the following · To determine the proximate and... Continue Reading

ABSTRACT  The place of adequate nutrition in the live of the young especially in the recently weaned cannot be overemphasized. The abrupt change in diet, leading to possible immune system weakness and disease conditions, is a focal point in the care of the young. This project examined serum globulin and bilirubin levels in weanling rats whose... Continue Reading

ABSTRACT The option of using microbes in the remediation of polluted sited have received wide acceptance due to its sustainability and environmental friendliness. This study is aimed at using the kinetic parameters (Vmax and Km) to assess the effect of organic and inorganic nitrogen sources on the performance of Pseudomonas sp., during the... Continue Reading

ABSTRACT The ethanolic leaves extracts of Hymenocardia acida was screened for anti-diabetic activity based on folklore and little or no work cited in literature. Hymenocardia acida (Family: Hymenocardiaceae) has a very high anti-diabetic potentials which appeared comparable to the control glibenclamide in alloxan induced diabetes mellitus. The... Continue Reading

ABSTRACT Twenty-two healthy albino mice were grouped into A, B, C, D, and E. Group A had six mice while groups B – E had four mice each. The mice were infected with Plasmodium berghei and the methanol extract of the leaves of Adansonia digitata was obtained by maceration extraction method. Phytochemical screening of the plant extract revealed... Continue Reading

TABLEOFCONTENTS ACKNOWLEDGEMENTS................................................................................................V LISTOFTABLES..........................................................................................................XIII... Continue Reading

In Africa traditional studies have shown that herbal medicine proves to be one of the best forms of treatment mensure to preventing or managing a disease condition. Sida coryembosa is a plant gotten from the eastern part of Nigeria Nnewe north to be precise and certain claims and attributes has been said about the plant in wound healing and a... Continue Reading

ABSTRACT Malaria is a significant public health problem in the world especially in in sub-Saharan Africa. One of the key contributory factors to the development and progression of malaria and its complications is oxidative stress, a condition characterized by increased production of free radicals or impaired antioxidant defence system.... Continue Reading

ABSTRACT This research was conducted to determine the concentrations of heavy metals and proximate composition of different cereals (maize, millet and rice). Two different samples each sold in two different markets (Ogbete and Gariki) in Enugu, were used for this work, using atomic, absorption spectrophotometer. The heavy metal screening of the... Continue Reading

ABSTRACT Diabetic mellitus is a metabolic disorder resulting from a defect in insulin secretion , insulin action or both . The deficiency of insulin leads to chronic hyperglycemia with disturbances of carbohydrate , fats and protein metabolism . Kigelia Africana is a sausage tree known to have medicinal values. The aim of this work is to evaluate... Continue Reading

Citrullus lanatus is medicinal plants believed to have many agents acting in different ways for the health benefits of human. This study investigated the acute phytochemical contents and effect of the methanol extract on weight changes, relative organ weight, hematological parameters and biomarkers of prostate dysfunction. The result indicated the... Continue Reading

ABSTRACT: Research and reviews are continually being carried out in order to discover cheaper and abundant plant sources of bioactive components which exhibit pharmacognostic and biochemical effects.... Continue Reading

ABSTRACT Kidney function parameters were evaluated in plasmodium berghei infected mice treated with crude methanol extracts of Azadirachta indica leaves in this study. A total of forty (40) male albino mice inoculated with quinine resistant strains of plasmodium berghei were randomized into nine (9) groups of (4) animals each while four additional... Continue Reading

ABSTRACT Nutritional and antinutritional content of ingredient used in preparing dambu were determined by proximate composition, vitamins, minerals and antinutritional contents analysis. Maize and Moringa flowers were used as the experimental samples and the work was conducted in triplicate which resulted in obtaining the experimental result in... Continue Reading

Abstract Soft drinks are consumed daily in Nigeria due to their characteristic taste, palatability, affordability and thirst quenching potential. This study quantifies the amount of electrolytes of Biochemical significance in selected soft drinks sold in Port Harcourt and their pH values. The samples included six frequently consumed soft drinks;... Continue Reading

TABLE OF CONTENTS Contents pages Cover page i Declaration ii Certification iii Dedication iv Acknowledgement v Abstract vi Table of content List of Figures List of Plates List of Tables CHAPTER ONE Itroduction 1 1.1 Justification 3 1.2 Objectives 4 1.3 Aim CHAPTER TWO Literature Review 2.1 Pesticide 2.1.1 Uses of pesticides 2.1.2 Types of... Continue Reading

ABSTRACT The consumption of the popular beverage coffee, increases day by day. However, upcoming brands of coffee with health benefits made by claims of the product ignites curiosity in the components of the coffee. The current study deals with the phytochemical analysis, antioxidant capacity and proximate analysis of Liven Alkaline Coffee,... Continue Reading

Effect of Chrysophyllum albidum pulp varieties on biochemical parameters was investigated using albino rat model. Thirty male Albino rats were divided into five groups of six rats each. A group served as the control while four groups served as the test groups A, B, C and D. Test groups A and B were placed on 5% and 25% respectively compounded feed... Continue Reading

ABSTRACT Musa paradisiaca is mainly grown in the tropical and subtropical countries and widely used for its nutritional values all over the world. The fruit as well as the peels and leaves are used to treat different diseases in human in traditional medicine. This study presents the mineral compositions and antifungal activity of ethanol... Continue Reading