EFFECTS OF ALUMINUM- MAGNESIUM ON THE ANTIPLASMODIAL ACTIVITY OF CHLOROQUINE PHOSPHATE IN MICE

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  • Department: Veterinary Medicine
  • Project ID: VEM0025
  • Access Fee: ₦5,000 ($14)
  • Pages: 91 Pages
  • Format: Microsoft Word
  • Views: 196
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ABSTRACT

Effect of stabilizing chloroquine phosphate in a synthetic Aluminium Magnesium silicate (Nanoparticles) on the antiplasmodial activity of the drug was investigated. Mice infected with Plasmodium berghei were treated with chloroquine phosphate at 7 mg/kg, 5 mg/kg and 3 mg/kg dose levels respectively. Two subgroups at each dose level were treated with chloroquine phosphate alone and with a drug formulation of 20% chloroquine phosphate in the synthetic Aluminium Magnesium Silicate (AMS) as an adjuvant. Percentage Plasmodium berghei parasitaemia (parasite/ml), Red blood cell (Rbc) count, Haemoglobin concentration (Hb), Rectal temperature (°C) and Body weight of mice in each of the treated groups and of the control were determined and compared. Mean parasitaemia, 4.15 0.26 of the group treated with 7mg/kg chloroquine phosphate alone was higher (P

EFFECTS OF ALUMINUM- MAGNESIUM ON THE ANTIPLASMODIAL ACTIVITY OF CHLOROQUINE PHOSPHATE IN MICE
For more Info, call us on
+234 8130 686 500
or
+234 8093 423 853

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  • Type: Project
  • Department: Veterinary Medicine
  • Project ID: VEM0025
  • Access Fee: ₦5,000 ($14)
  • Pages: 91 Pages
  • Format: Microsoft Word
  • Views: 196
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    Type Project
    Department Veterinary Medicine
    Project ID VEM0025
    Fee ₦5,000 ($14)
    No of Pages 91 Pages
    Format Microsoft Word

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