+234 813 0686 500
+234 809 3423 853
info@grossarchive.com
+234 813 0686 500
info@grossarchive.com

Project Topic: EFFECT OF SOLANUM MACROCARPON AND ANTI-DIABETIC DRUG GLIBENCLIMIDE ON SOME BLOOD PARAMETERS OF ALLOXAN INDUCED DIABETIC RATS

  • Type: Project
  • Department: Physiology
  • Project ID: PGY0007
  • Price: ₦3,000 ($20)
  • Pages: 69 Pages
  • Format: Microsoft Word
  • Views: 471

For more Info, call us on
+234 8130 686 500
or
+234 8093 423 853


Diabetes mellitus commonly known as diabetes is a group of metabolic disorder characterized by high blood sugar level over a prolonged period (WHO,2014)


This  research is aimed at investigating effect of solanum macrocapon and Anti-diabetic drug glibenclamide on some blood parameters of alloxan induced diabetic rats.


The effects of four eggplant varieties on haematological indices and weight of organs in albino rats were evaluated. A total of 30 albino rats were randomly distributed into six major groups of treatment, Group A were administered with Feed and water only, B with Feed and water only C with 5ml/kg of Glibenclamide, D with 250mg/kg of aqueous extract, E with 500mg/kg of aqueous extract and F with 750mg/kg  of aqueous extract.


Result from this study showed that the induction of diabetes to the experimental animals led to an increase in the size of the liver, pancrease, spleen, kidney, duodenum and stomach. The treatment with glibenclimide led to a reversal in the organ mass, however administration with aqueous extract of Solanum macrocarpon was more potent than Glibenclimide at 500 and 750mg/kg.


The heamatological profile of experimental animals was also investigated. There were alterations in the level of blood parameters. There was an increase in the level of WBC, HBG, NEU, LYM, and MONO, HCT, PLT in diabetic animals when compared with the control animals. The treatment with Glibenclimde and aqueous extract Solanum macrocarpon. Aqueous extract of Solanum macrocarpon only was found to be more effect in reversing these disorders at 500mg/kg.


The administration of aqueous extract of Solanum macrocarpon was found to have therapeutic effect which is evident in its ability to reverse organ weight and pathological alterations.


EFFECT OF SOLANUM MACROCARPON AND ANTI-DIABETIC DRUG GLIBENCLIMIDE ON SOME BLOOD PARAMETERS OF ALLOXAN INDUCED DIABETIC RATS
For more Info, call us on
+234 8130 686 500
or
+234 8093 423 853

Share This
  • Type: Project
  • Department: Physiology
  • Project ID: PGY0007
  • Price: ₦3,000 ($20)
  • Pages: 69 Pages
  • Format: Microsoft Word
  • Views: 471
Payment Instruction
Bank payment for Nigerians, Make a payment of ₦ 3,000 to

Bank GTBANK
gtbank
Account Name Obiaks Business Venture
Account Number 0211074565

Bitcoin: Make a payment of 0.0003 to

Bitcoin(Btc)

btc wallet
Copy to clipboard Copy text

500
Leave a comment...

    Details

    Type Project
    Department Physiology
    Project ID PGY0007
    Price ₦3,000 ($20)
    No of Pages 69 Pages
    Format Microsoft Word

    Related Works

    Diabetes mellitus commonly known as diabetes is a group of metabolic disorder characterized by high blood sugar level over a prolonged period (WHO,2014) This research is aimed at investigating effect of solanum macrocapon and Anti-diabetic drug glibenclamide on some blood parameters of alloxan induced diabetic rats. The effects of four eggplant... Continue Reading
    TABLE OF CONTENT CHAPTER ONE 1.0 INTRODUCTION 1.1 AIMS AND OBJECTIVES OF THE RESEARCH CHAPTER TWO 2.0 LITERATURE REVIEW 2.1 SCIENTIFIC CLASSIFICATION OF SENNA TORA 2.2 DESCRIPTION OF SENNA TORA 2.3 SOME COMMON NAMES OF SENNA TORA 2.4 GEOGRAPHICAL DISTRIBUTION OF SENNA TORA 2.5 GROWTH REQUIREMENTS OF SENNA TORA 2.6 PROPAGATION OF SENNA TORA 2.7... Continue Reading
    ABSTRACT The ethanolic leaves extracts of Hymenocardia acida was screened for anti-diabetic activity based on folklore and little or no work cited in literature. Hymenocardia acida (Family: Hymenocardiaceae) has a very high anti-diabetic potentials which appeared comparable to the control glibenclamide in alloxan induced diabetes mellitus. The... Continue Reading
    Anti-diabetic and Anti-oxidant potentials of Aqueous Extract of Eucalyptus Globulus in experimentally induced diabetic rats.... Continue Reading
    This research project studied the effect of ethanolic leaf extract of Dialium guineense Willd (Fabaceae) on oral glucose tolerance in mice and alloxan-induced diabetic female rats.  The ethanolic leaf extract was prepared by marcerating 500g of the dried, milled leaves of D. guineense in 3L of 96% ethanol in a suitable sized plastic bucket/bowl... Continue Reading
    ABSTRACT Diabetic mellitus is a metabolic disorder resulting from a defect in insulin secretion , insulin action or both . The deficiency of insulin leads to chronic hyperglycemia with disturbances of carbohydrate , fats and protein metabolism . Kigelia Africana is a sausage tree known to have medicinal values. The aim of this work is to evaluate... Continue Reading
    TABLE OF CONTENT Title Page Title Page - - - - - - - - - - i Dedication - - - - - - - - - - ii Declaration - - - - - - - - - - iii Certification - - - - - - - - - - iv Acknowledgement - - - - - - - - - v Table of Content - - - - - - - - - vii List of Table - - - - - - - - - xi List of Figures - - - - - - - - - xii Abstract - - - - - - - - - - xiii... Continue Reading
    COMPARATIVE STUDY OF THE EFFECT OF ETHANOLIC EXTRACT OF Lonchocarpus cyanescens (ELU) AND Dialium guineense (ICHEKU) ON THE LIPID PROFILE OF STREPTOZOTOCIN INDUCED DIABETIC ALBINO RATS ABSTRACT This study was carried out to determine the effect of ethanoic extract of Lonchocarpus cyanescens and Dialium guineense on the lipid profile of... Continue Reading
    Call Us
    Get this work
    whatsappWhatsApp Us