ABSTRACT
A total of 50 blood (30 pregnant and 20 HIV) samples were obtained from pregnant women and PLWHA attending clinic at UNTH Ituku-ozalla. Samples were screened for hepatitis c viral infection using the rapid one step hepatitis C virus test strip. Two (6.66%) pregnant women were positive and four (20%) HIV patients were positive for Hepatitis C, giving an overall prevalence rate of (26.7%). The infection was the same in male (3) and in female (3). Those aged 23-34 years recorded a higher prevalence of (20%) than those in the age group 19-23. This higher prevalence of hepatitis C suggests that pregnant women and PLWHA may be at risk of hepatitis due to hepatitis C virus. Therefore routine screening of pregnant women and PLWHA should be instituted for early diagnosis and management of cases.

TABLE OF CONTENT
Title page……………………………………………………….i
Certification…………………………………………………….ii
Dedication………………………………………………………iii
Acknowledgement………………………………………………iv
Table of content…………………………………………………v
List of table……………………………………………………..vii
Abstract…………………………………………………………viii
 Chapter one
1.1 Introduction………………………………………………….1
1.2 Objectives……………………………………………………4

Chapter two
2.1 Mode of transmission and risk factors …………………........5
2.2 Pathogenesis and incubation period…………………………..7
2.3 Epidemiology…………………………………………………8
2.4 Signs and symptoms………………………………………….9
2.5 Diagnosis……………………………………………………..9
2.6 Prevention and control………………………………………11
2.7 Treatment……………………………………………………12
2.8 Hepatitis C virus and pregnancy…………………………….12
2.9 Hepatitis C virus and HIV…………………………………...16

 Chapter three
3.1 Material……………………………………………………..18
3.2 Study population……………………………………………18
3.3 Sample collection…………………………………………..18
3.4 Method……………………………………………………..18

 Chapter four
4.1 Results………………………………………………………20

 Chapter five
5.1 Discussion………………………………………………….26
5.2 Conclusion………………………………………………….26
5.3 Recommendation…………………………………………...27
References………………………………………………………28