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ABSTRACT Azadirachta indica, commonly known as Neem, has attracted worldwide prominence in recent years as a cynosure of modern medicine owing to its wide range of medicinal properties. This study was carried out to investigate the phytochemical properties and antioxidant activity of the multi-solvent (methanol, ethanol and hexane) extracts of the... Continue Reading
ABSTRACT Azadirachta indica, commonly known as Neem, has attracted worldwide prominence in recent years as a cynosure of modern medicine owing to its wide range of medicinal properties. This study was carried out to investigate the phytochemical properties and antioxidant activity of the multi-solvent (methanol, ethanol and hexane) extracts of the... Continue Reading
ABSTRACT Diabetic mellitus is a metabolic disorder resulting from a defect in insulin secretion , insulin action or both . The deficiency of insulin leads to chronic hyperglycemia with disturbances of carbohydrate , fats and protein metabolism . Kigelia Africana is a sausage tree known to have medicinal values. The aim of this work is to evaluate... Continue Reading
ABSTRACT Diabetic mellitus is a metabolic disorder resulting from a defect in insulin secretion , insulin action or both . The deficiency of insulin leads to chronic hyperglycemia with disturbances of carbohydrate , fats   and protein metabolism . Kigelia Africana is a sausage tree known to have medicinal values. The aim of this work is to... Continue Reading
ABSTRACT This research investigated the phytochemical and anti-inflammatory properties of methanol extract of Crateva adansonii stem bark. Although several edible and non-edible plants parts are used in inflammatory treatment, many record has been found of the use of Crateva adansonii stem bark. For this research, fresh stem bark of Crateva... Continue Reading
ABSTRACT Inflammation is a complex biological response of vascular tissue to harmful stimuli such as pathogen, damage cells or irritants. The urgency generated by in increased rate of stroke, atheroselerosis attributed to prolong use of... Continue Reading
ABSTRACT This research investigated the phytochemical and anti-inflammatory properties of methanol extract of Crateva adansonii stem bark. Although several edible and non-edible plants parts are used in inflammatory treatment, many record has been found of the use of Crateva adansonii stem bark. For this research, fresh stem bark of Crateva... Continue Reading
ABSTRACT This research investigated the phytochemical and anti-inflammatory properties of methanol extract of Crateva adansonii stem bark. Although several edible and non-edible plants parts are used in inflammatory treatment, many record has been found of the use of Crateva adansonii stem bark. For this research, fresh stem bark of Crateva... Continue Reading
ABSTRACT This research investigated the phytochemical and anti-inflammatory properties of methanol extract of Crateva adansonii stem bark. Although several edible and non-edible plants parts are used in inflammatory treatment, many record has been... Continue Reading
ABSTRACT This research investigated the phytochemical and anti-inflammatory properties of methanol extract of Crateva adansonii stem bark. Although several edible and non-edible plants parts are used in inflammatory treatment, many record has been found of the use of Crateva adansonii stem bark. For this research, fresh stem bark of Crateva... Continue Reading
Morinda lucida is a tropical West African evergreen shrub or small to medium sized rainforest tree, having brown colored bark, white flowers and yellowish ellipsoid seeds. It is widely used in traditional medicine systems of different countries. This study was designed to carry out the preliminary phytochemical screening and evaluation antioxidant... Continue Reading
Morinda lucida is a tropical West African evergreen shrub or small to medium sized rainforest tree, having brown colored bark, white flowers and yellowish ellipsoid seeds. It is widely used in traditional medicine systems of different countries. This study was designed to carry out the preliminary phytochemical screening and evaluation antioxidant... Continue Reading
Abstract The research on Mucuna pruriens was to know its ameliorative efficacy on the kidney markers of malaria infected mice. The antimalaria effect was evaluated against Plasmodium berghei stain of 25 mice.The twenty five (25) adult albino mice of both sexes which weighed 20g-36g were grouped into five(1-5) of five mice per group which was used... Continue Reading
ABSTRACT Adansonia digitata has popular ethnomedicinal application in the treatment of malaria in sub-Saharan Africa. The present study sought to investigate the antimalarial and antioxidant effects of methanol and flavonoid-rich extracts of the stem bark on Plasmodium berghei-infected mice in vivo. Thirty-five male mice, weighing 18-20 g and... Continue Reading
ABSTRACT Pausinystalia yohmibe is a member of thefamilyRubiaceae. It is a valuable medicinal tree, distributed in evergreen closed canopy forests in West Africa.  It is traditionally used for treatment mostly on erectile dysfunction. This research was carried out to evaluate the immunomodulatory effect of ( Pausinystalia yohmibe) stem bark... Continue Reading
Methanol extract of Gloriosa superba in this research was adopted due to the presence of photochemicals present in the plant. This photochemicals are known to act as antioxidants and anti tumor agent but it is not yet known if the activity of the plant is through the mitochondria mediated pathway, caspase activation and induction of apoptosis... Continue Reading
Methanol extract of Gloriosa superba in this research was adopted due to the presence of photochemicals present in the plant. This photochemicals are known to act as antioxidants and anti tumor agent but it is not yet known if the activity of the plant is through the mitochondria mediated pathway, caspase activation and induction of apoptosis... Continue Reading
Activation of caspase 3&9 by methanol extract of Gloriosa superba  ABSTRACT Mitochondrion is the key regulator in cellular energy homeostasis and plays a central role in determining cell apoptotic process; it is therefore regarded as a vital target for cancer chemotherapy.   Cancer is obviously one of the most common areas where demand for... Continue Reading
Activation of caspase 3&9 by methanol extract of Gloriosa superba  ABSTRACT Mitochondrion is the key regulator in cellular energy homeostasis and plays a central role in determining cell apoptotic process; it is therefore regarded as a vital target for cancer chemotherapy.   Cancer is obviously one of the most common areas where demand for... Continue Reading
ABSTRACT Inflammation is a complex biological response of vascular tissue to harmful stimuli such as pathogen, damage cells or irritants. The urgency generated by in increased rate of stroke, atheroselerosis attributed to prolong use of cyclooxygenase-1 and 2 inhibitors have acceralated anti-inflammatory drug research over the last decade while... Continue Reading
ABSTRACT Inflammation is a complex biological response of vascular tissue to harmful stimuli such as pathogen, damage cells or irritants. The urgency generated by in increased rate of stroke, atheroselerosis attributed to prolong use of cyclooxygenase-1 and 2 inhibitors have acceralated anti-inflammatory drug research over the last decade while... Continue Reading
ABSTRACT Inflammation is a complex biological response of vascular tissue to harmful stimuli such as pathogen, damage cells or irritants. The urgency generated by in increased rate of stroke, atheroselerosis attributed to prolong use of cyclooxygenase-1 and 2 inhibitors have acceralated anti-inflammatory drug research over the last decade while... Continue Reading
ABSTRACT The chemotherapy of gastrointestinal helminthiasis relies mainly on the use of anthelmintics. However, concerns over drug resistance have encouraged the search for new drug leads. This project report focused on evaluating the toxicity and anthelminthic effect produced in vitro and in vivo by the methanol extract of Duranta erecta fruits.... Continue Reading
ABSTRACT Inflammation is a complex biological response of vascular tissue to harmful stimuli such as pathogen, damage cells or irritants. The urgency generated by in increased rate of stroke, atheroselerosis attributed to prolong use of cyclooxygenase-1 and 2 inhibitors have acceralated anti-inflammatory drug research over the last decade while... Continue Reading
ABSTRACT Inflammation is a complex biological response of vascular tissue to harmful stimuli such as pathogen, damage cells or irritants. The urgency generated by in increased rate of stroke, atheroselerosis attributed to prolong use of cyclooxygenase-1 and 2 inhibitors have acceralated anti-inflammatory drug research over the last decade while... Continue Reading
ABSTRACT Leaf of Vernonia amygdalina has been shown to have hypoglycemic activity. This may be as a result of the presence of secondary metabolites as its constituents. The major secondary metabolites present in the leaf are tannins, carbohydrates, reducing sugars, glycosides, steroids and proteins. This work was designed to identify these... Continue Reading
Plants have been utilized for medicinal reasons since the dawn of time. Pharmacologists and organic chemists have synthesized a wide range of intriguing chemical compounds from medicinal plants in recent decades, which have shown to be quite useful in the practice of optometry and medicine. There is now an increase in global demand for the use of... Continue Reading
Abstract a comparative study was done on the physico-chemical and antioxidant properties of some culinary herbs and local spices. Piper Guiness (Uziza), Xylopia aethopica (Uda), Monodora Myristica (Ehuru) and TrtraleuraTetraopera (Oshsho).  The proximate analysis of these spices  were done to determine their moisture content, ash... Continue Reading
PIPE GUIEENSE (UZIZA) XYLPIA AETHPICA (UDA) MONODORA MYRISTICA (EHURU) TETRAPELURA TETRAPTERA (OSHOSHO) Abstract a comparative study was done on the physico-chemical and antioxidant properties of some culinary herbs and local spices. Piper Guiness (Uziza), Xylopia... Continue Reading
ABSTRACT The methanol extract of Ocimum basilicum (Scent leaf) was greenish in colour and increases in concentration through evaporation process which turns the extract to thick and dark green colouration. The percentage parasitaemia growth increases consecutively for seven (7) days with 7th day result having the highest parasite growth of 18.73%.... Continue Reading
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