IN VITRO ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL PROPERTIES OF METHANOL, ETHANOL AND HEXANE EXTRACTS OF AZADIRACHTA INDICA LEAVES.

  • Type: Project
  • Department: Bio-Chemistry
  • Project ID: BCH0218
  • Access Fee: ₦5,000 ($14)
  • Pages: 81 Pages
  • Format: Microsoft Word
  • Views: 525
  • Report This work

For more Info, call us on
+234 8130 686 500
or
+234 8093 423 853

ABSTRACT

Azadirachta indica, commonly known as Neem, has attracted worldwide prominence in recent years as a cynosure of modern medicine owing to its wide range of medicinal properties. This study was carried out to investigate the phytochemical properties and antioxidant activity of the multi-solvent (methanol, ethanol and hexane) extracts of the leaves of Azadirachta indica of Meliaceae family. The extracts were investigated for phytochemical constituents such as tannins, saponins, alkaloids, total flavonoids, total phenols and proanthocyanidin, while the in vitro antioxidant activity was determined using DPPH scavenging assay, FRAP assay, metal ion chelating assay and reducing power assays. Total phenol content of extracts were also determined by Folin-Ciocalteu method. Experimental results obtained for phytochemical studies revealed that flavonoids content is highest in the methanol extract (79.10±1.15 mg QE/g extract), while the ethanol extract had the lowest content. Also, the methanol extract of A. indica leaves has the highest fraction of crude extract, highest phenol content (342±10.2 mg GAE/g extract), highest tannin content (97.83±3.49 mg TAE/g extract), highest proanthocyanidin content (13.17±2.85 mg AAE/g extract). Qualitative studies show the presence of the various phytochemicals in varying amounts; however, cardiac glycosides were absent in the hexane and ethanol extracts, alkaloids were absent in the ethanol extract, while saponins were absent in the hexane extract. Similarly, IC50 values of the ethanolic extract of A. indica leaves (IC50 values of 81.62µg/ml and 83.29µg/ml) were lower than other extracts for DPPH scavenging assay and metal ion chelating respectively. The various extracts of A. indica leaves may be exploited for clinical medicine as potent factors because of their high antioxidant activity.

IN VITRO ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL PROPERTIES OF METHANOL, ETHANOL AND HEXANE EXTRACTS OF AZADIRACHTA INDICA LEAVES.
For more Info, call us on
+234 8130 686 500
or
+234 8093 423 853

Share This
  • Type: Project
  • Department: Bio-Chemistry
  • Project ID: BCH0218
  • Access Fee: ₦5,000 ($14)
  • Pages: 81 Pages
  • Format: Microsoft Word
  • Views: 525
Payment Instruction
Bank payment for Nigerians, Make a payment of ₦ 5,000 to

Bank GTBANK
gtbank
Account Name Obiaks Business Venture
Account Number 0211074565

Bitcoin: Make a payment of 0.0005 to

Bitcoin(Btc)

btc wallet
Copy to clipboard Copy text

500
Leave a comment...

    Details

    Type Project
    Department Bio-Chemistry
    Project ID BCH0218
    Fee ₦5,000 ($14)
    No of Pages 81 Pages
    Format Microsoft Word

    Related Works

    ABSTRACT Azadirachta indica, commonly known as Neem, has attracted worldwide prominence in recent years as a cynosure of modern medicine owing to its wide range of medicinal properties. This study was carried out to investigate the phytochemical properties and antioxidant activity of the multi-solvent (methanol, ethanol and hexane) extracts of the... Continue Reading
    ABSTRACT Azadirachta indica, commonly known as Neem, has attracted worldwide prominence in recent years as a cynosure of modern medicine owing to its wide range of medicinal properties. This study was carried out to investigate the phytochemical properties and antioxidant activity of the multi-solvent (methanol, ethanol and hexane) extracts of the... Continue Reading
    ABSTRACT Comparative assessment of the phytochemical content and antioxidant potential of Azadirachta indica (neem) and Parquetina nigrescens (bullock) is the aim of this study. In order to achieve this, both plants were harvested from the botanical garden, University of Ibadan. The leaves were removed from the stem, washed with running water to... Continue Reading
    ABSTRACT Comparative assessment of the phytochemical content and antioxidant potential of Azadirachta indica (neem) and Parquetina nigrescens (bullock) is the aim of this study. In order to achieve this, both plants were harvested from the botanical garden, University of Ibadan. The leaves were removed from the stem, washed with running water to... Continue Reading
    ABSTRACT T he present study investigated herb-drug interactions involving cold water extract of Azadirachta indica (neem) leaves, with five classes of antibiotics, namely: Tetracyclines - Tetracycline (TET) and Doxycycline POX); I Penicillins - Penicillin G(PG) and Ampicillin (AMP); Cephalosporins - Cefuroxime (CF); Arninoglycosides -Gentamicycin... Continue Reading
    ABSTRACT This study focused on the comparative study of the phytochemical constituents, in vitro antioxidant activity of the stem bark and seed oil extracts of Allanblackia floribunda. The phytochemical screening revealed that both extracts contain flavonoids, tannins, cardiac glycosides, alkaloids and saponins while terpenoids are absent in the... Continue Reading
    ABSTRACT This study focused on the comparative study of the phytochemical constituents, in vitro antioxidant activity of the stem bark and seed oil extracts of Allanblackia floribunda. The phytochemical screening revealed that both extracts contain flavonoids, tannins, cardiac glycosides, alkaloids and saponins while terpenoids are absent in the... Continue Reading
    ABSTRACT This study focused on the comparative study of the phytochemical constituents, in vitro antioxidant activity of the stem bark and seed oil extracts of Allanblackia floribunda. The phytochemical screening revealed that both extracts contain flavonoids, tannins, cardiac glycosides, alkaloids and saponins while terpenoids are absent in the... Continue Reading
    ABSTRACT Twenty-two healthy albino mice were grouped into A, B, C, D, and E. Group A had six mice while groups B – E had four mice each. The mice were infected with Plasmodium berghei and the methanol extract of the leaves of Adansonia digitata was obtained by maceration extraction method. Phytochemical screening of the plant extract revealed... Continue Reading
    ABSTRACT Twenty-two healthy albino mice were grouped into A, B, C, D, and E. Group A had six mice while groups B – E had four mice each. The mice were infected with Plasmodium berghei and the methanol extract of the leaves of Adansonia digitata was obtained by maceration extraction method. Phytochemical screening of the plant extract revealed... Continue Reading
    Call Us
    whatsappWhatsApp Us