A COMPARATIVE STUDY BETWEEN COMPUTED TOMOGRAPHY AND MAGNETIC RESONANCE IMAGING IN THE DIAGNOSIS OF BRAIN TUMOR USING NATIONAL HOSPITAL, ABUJA AS CASE STUDY
A COMPARATIVE STUDY BETWEEN COMPUTED TOMOGRAPHY AND MAGNETIC RESONANCE IMAGING IN THE DIAGNOSIS OF BRAIN TUMOR USING NATIONAL HOSPITAL, ABUJA AS CASE STUDY
This study sought to equip clinician’s on the imaging modality of choice between CT and MRI in the diagnosis of brain tumor. The comparison of the two imaging modalities was accessed using biopsy as goal standard. This research study involved 40 patients who underwent CT, MRI and biopsy one at a time in National hospital, Abuja. Data were collected via secondary source using patient’s folder; hospital records. The result revealed that MRI which has an accuracy, sensitivity and specificity of 67.5%, 65.22% and 70.65% respectively is more accurate than CT which had a sensitivity and specificity of 15%, 13.04% and 17.65% respectively in the diagnosis of brain tumour. Knowledge of the clinician on which modality of choice to use is evaluated.
TABLE CONTENT
Title page
Approval page
Certification
Dedication
Acknowledge
List of tables
Abstract
Table of content
Chapter One
1.1 Introduction
1.2 Statement of problem
1.3 General objective
1.4 Specific objective
1.5 Hypothesis
1.6 Significance of study
1.7 Scope of study
1.8 Literature review
Chapter Two
2.1 CT and its principles of operation
2.2 MRI and its principles of operation
2.3 Anatomy and physiology of the brain
2.4 Pathophysiology of brain tumuor
2.5 Conditions that mimic Brain tumour
2.6 Cause, symptoms and types of Brain tumour
2.7 How CT of the brain is done and clinical presentation of Brain tumour on CT radiograph
2.8 How MRI of the brain is done and clinical presentation of Brain tumour MRI radiograph
Chapter Three
3.0 Design of the study
3.2 Population
3.2.1 Area of study
3.2.2 Target population
3.2.3 Subject selection criteria
3.3 Method of data collection
3.3.1 Equipments
3.3.2 Procedure for data collection
3.4 Data analysis
Chapter Four:
Data Presentation
Chapter Five: Discussion, Recommendations, Summary of Findings and Conclusion
5.1 Discussion
5.2 Summary of findings
5.3 Recommendations
5.4 Conclusion
5.5 Areas of further studies
5.6 Limitations of the study
References
Appendix
INTRODUCTION
Brain tumours are abnormal and uncontrolled proliferation of cells1. Some originate in the brain itself, in which they are termed primary. Others spread to this location from somewhere else in the body through metastases and are termed secondary. Primary brain tumours do not spread to other body sites, and can be malignant or benign. Secondary brain tumours are always malignant. Because the space inside the skull is limited, their growth increase intracranial pressure, and may, cause edema, reduced blood flow, and displacement with consequent degeneration, of healthy tissue that controls vital function.2
Any brain tumor is inherently serious and life-threatening because of its invasive and infiltrative character in the limited space of the intracranial cavity3. However, brain tumors (even malignant ones) are not invariably fatal, especially lipomas which are inherently benign. Brain tumors or intracranial neoplasms can be cancerous (malignant) or non-cancerous (benign); however, the definitions of malignant or benign neoplasms differ from those commonly used in other types of cancerous or non-cancerous neoplasms in the body. Its threat level depends on the combination of factors like the type of tumor, its location, its size and its state of development. Because the brain is well protected by the skull, the early detection of a brain tumor only occurs when diagnostic tools are directed at the intracranial cavity. Usually detection occurs in advanced stages when the presence of the tumor has caused unexplained symptoms.
A good evaluation of the patient with a suspected brain tumour needs a complete history, exact physical examinations especially neurologic ones, and suitable diagnostic neuroimaging studies. The differential diagnosis of patients with signs and symptoms of brain tumours includes both neoplastic and non-neoplastic conditions.4
Computed tomography is the most widespread diagnostic tool for the localization and staging of brain tumour. It has an advantage of being widely available. Computed tomography is faster than magnetic resonance imaging making it study of choice in cases of trauma and emergencies.
MRI provides detailed info about brain tumour anatomy, cellular structure and vascular supply, making it an important tool for effective diagnosis, treatment and monitoring of brain tumour5. MRI does not use ionizing radiation, and thus preferred over CT in patient requiring multiple imaging examinations.
A COMPARATIVE STUDY BETWEEN COMPUTED TOMOGRAPHY AND MAGNETIC RESONANCE IMAGING IN THE DIAGNOSIS OF BRAIN TUMOR USING NATIONAL HOSPITAL, ABUJA AS CASE STUDY
This study sought to equip clinician’s on the imaging modality of choice between CT and MRI in the diagnosis of brain tumor. The comparison of the two imaging modalities was accessed using biopsy as goal standard. This research study involved 40 patients who underwent CT, MRI and biopsy one at a time in National hospital, Abuja. Data were... Continue Reading
ABSTRACT Objective: To evaluate the common MRI findings in patients with neurologic disorders. Method: A retrospective study of 106 patients with neurologic disorders was carried out and their respective findings carefully tabulated according to their age and sex. Results: MRI showed small multifocal lesions hyperintense on T2 weighted images and... Continue Reading
ABSTRACT Background: Computed tomography has become an important tool in medical imaging to supplement conventional x-rays examination and ultrasonography. Aim: To describe the pattern of abdomino-pelvic computed tomography findings in the adult Nigerian population. (A case study EKO Hospital, Ikeja). Patients and Method: A retrospective study of... Continue Reading
ABSTRACT The aim of this research is to evaluate the diagnostic yield of MRI in the diagnosis of Brain tumour, at National Hospital, Garki Abuja. It is a retrospective study, which evaluated the diagnostic yield of MRI in the diagnosis of Brain tumour, the sensitivity, Specificity, and accuracy of the Imaging Procedure in the Management of Brain... Continue Reading
A COMPARATIVE STUDY OF EXPENDITURE CONTROLS METHODS IN GOVERNMENT OWNERS AND PRIVATELY OWNED HOSPITAL (A CASE STUDY OF THE UNIVERSITY OF NIGERIA TEACHING HOSPITAL.ENUGU AND TORONTO HOSPITAL AND MATERNITY ONITSHA) PROPOSAL This research work is on expenditure controls method in government owned hospitals, a case study of university of Nigerian... Continue Reading
A COMPARATIVE STUDY OF EXPENDITURE CONTROLS METHODS IN GOVERNMENT OWNERS AND PRIVATELY OWNED HOSPITAL (A CASE STUDY OF THE UNIVERSITY OF NIGERIA TEACHING HOSPITAL ENUGU AND TORONTO HOSPITAL AND MATERNITY ONITSHA) PROPOSAL This research work is on expenditure controls method in government owned hospitals, a case study of university of Nigerian... Continue Reading
CHAPTER ONE INTRODUCTION 1.1 Background to the Study Employees are the assets of any organization and compensation had been seen to be a vital instrument in employee performance. A well rewarded employee feels that he/she is being valued by the company that he/she is working for. They are also encouraged to work harder and better if they are aware... Continue Reading
ABSTRACT This is a prospective non experimental survey study design aimed at describing radiographic care of trauma patients: case study of UNTH and NOHE. The questionnaires for the study were distributed among radiographers in the above mentioned hospitals. The objectives and purpose of the research were explained by the researcher. Medical... Continue Reading