Recent Bio-Chemistry Project Topics and Materials (Page 5)

ABSTRACT Human systemic fungal infections have increased in the past decade due to the dramatic increase in immunocompromised patients hence the emergence of resistant fungal strains. It is therefore necessary to discover new antifungal compounds with novel mode of action. This study was aimed at isolating and characterizing antifungal agents from... Continue Reading

ABSTRACT Current efforts to eliminate malaria worldwide are soaring and one of the approaches to this is the mass screening of medicinal plants for their possible potential anti-malarial property. The current study conducted was to determine the effect of one such plant, Cryptolepis sanguinolenta on gametocyte development. In vitro growth... Continue Reading

ABSTRACT The suitability o f five Schistosoma genus-specific monoclonal antibodies (MoAbs) (Sh3/34.10, Sh3/38.2, Sh4/14.3, Sh5/32.30 and Sh5/34.10) in detecting schistosome antigens in infected human and cattle was evaluated. These antibodies were employed in various diagnostic assays to diagnose human and animal schistosomiasis. Extant MoAb... Continue Reading

ABSTRACT This study assessed the phytochemical and nutrient compositions of edible yam species Dioscorea rotundata 1, Dioscorea rotundata 2, Dioscorea rotundata 3, Dioscuri rotundata 4, Dioscorea Cayenensis, Dioscorea alata, Dioscorea dumentorum and Dioscorea bulbifera in Southeastern Nigeria. The phytochemical and nutrient (proximate, minerals,... Continue Reading

ABSTRACT Among medicinal plants, Picralima nitida is well investigated and has been shown to possess renal and hepatoprotective activities. The present study was conducted to investigate the chemoprotective effect of methanol extract of Picralima nitida leaves on carbon tetrachloride-induced oxidative stress in albino rats. Thirty (30) Wistar... Continue Reading

ABSTRACT The impact of pollution due to gas flaring on individuals native to Ebocha in Niger Delta Area was investigated. One hundred and five apparently healthy individuals between 21-70years who consented for the study were screened, seventy five individuals from Ebocha and thirty from Nsukka-a control location with no history of petroleum... Continue Reading

ABSTRACT The burden of hyperlipidemia is on the rise globally especially in many low income countries like Uganda. Management of this metabolic disorder mainly involves dietary and behavioral therapies, which are often met with poor results as they require time and discipline from the patients. The chemotherapeutic options available are expensive,... Continue Reading

ABSTRACT The burden of hyperlipidemia is on the rise globally especially in many low income countries like Uganda. Management of this metabolic disorder mainly involves dietary and behavioral therapies, which are often met with poor results as they require time and discipline from the patients. The chemotherapeutic options available are expensive,... Continue Reading

 PHYTOCHEMICAL ANALYSIS OF FLUTED PUMPKINLEAVES (TELFAIRA OCCIDENTALIS) ABSTRACT Fluted pumpkin leaves (Telfaira occidentalis) is a well known vegetable used by the Western Ngerian and generally called “ugu” in igbo land. This study was carried out to qualitatively determine the presence of phytochemicals in it. This study was carried out... Continue Reading

The presence study aimed to investigate the phytochemical and heavy metals level in selected vegetables grown in Kalambaina area ,the phytochemical were determined using analytical methods and the heavy metals (Cd, Pb, Zn, Ni, Cr and Cu) concentration in vegetables and water were determined using atomic absorption spectroscopy (AAS). The study... Continue Reading

ABSTRACT Exposure to environmental toxicant was known to cause neuronal disorders in humans. Hence, the present study evaluates the toxic effect of leachate (an environmental toxicant) in the synaptosomes of female rats and the reversal effect of phenolic-rich fraction from Croton zambesicus. Fifty animals were divided into five groups. Group I... Continue Reading

ABSTRACT Exposure to environmental toxicant was known to cause neuronal disorders in humans. Hence, the present study evaluates the toxic effect of leachate (an environmental toxicant) in the synaptosomes of female rats and the reversal effect of phenolic-rich fraction from Croton zambesicus. Fifty animals were divided into five groups. Group I... Continue Reading

ABSTRACT Phytochemical and Proximate analyses of two samples of Aloe vera from variable habitats (highland and lowland) of Sokoto metropolis were accessed. Phytochemical and proximate compositions of highland sample were 8.16mg/100g of Saponin, 3.40mg/100g of Glycoside, 1.80mg/100g of Alkaloid and 2.50mg/100g of Anthraquinone. Proximate... Continue Reading

ABSTRACT This study focused on the comparative study of the phytochemical constituents, in vitro antioxidant activity of the stem bark and seed oil extracts of Allanblackia floribunda. The phytochemical screening revealed that both extracts contain flavonoids, tannins, cardiac glycosides, alkaloids and saponins while terpenoids are absent in the... Continue Reading

ABSTRACT Azadirachta indica, commonly known as Neem, has attracted worldwide prominence in recent years as a cynosure of modern medicine owing to its wide range of medicinal properties. This study was carried out to investigate the phytochemical properties and antioxidant activity of the multi-solvent (methanol, ethanol and hexane) extracts of the... Continue Reading

ABSTRACT This study focused on the comparative study of the phytochemical constituents, in vitro antioxidant activity of the stem bark and seed oil extracts of Allanblackia floribunda. The phytochemical screening revealed that both extracts contain flavonoids, tannins, cardiac glycosides, alkaloids and saponins while terpenoids are absent in the... Continue Reading

Abstract The immunomodulatory effect of the ethanolic leaf extract of Phyllantus amarus on wistar rats was investigated. Twenty eight (28) male animals were used for the study. The animals were divided into four (4) groups of seven (7) animals each. Group 1... Continue Reading

Abstract   The effect of Shea butter rich diet on gentamicin induced nephrotoxicity in rats was determined. Thirty (30) male and female albino rats grouped into 6 (normal, negative, positive, 10%, 20% and 30% Shea butter rich diet groups respectively) of 5 rats each were used for the study. Phytochemical analysis was carried out on the Shea... Continue Reading

The work was aimed at investigating the effect of Cocus nucifera on male albino rats. A number of rats were placed in groups and all groups were fed Cocus nucifera except one group, the control group. Analysis of results was done with ANOVA.... Continue Reading

TABLES OF CONTENT TITLE PAGE i CERTIFICATION ii DEDICATION iii ACKNOWLEDGEMENT IV TABLES OF CONTENT V ABSTRACT VI CHAPTER ONE 1.0 INTRODUCTION 1.1 LITERATURE REVIEW 1.2 THE LIVER 1.2.1 CARBON TETRACHLORIDE 1.3.0 LIVER FUNCTION TEST 1.3.1 TOTAL CHOLESTEROL 1.3.6 FUNCTIONS OF THE LIVER 1.6.0 LIPID PEROXIDATION 1.8.2 BOTANICAL DESCRIPTION OF DENNETIA... Continue Reading

TABLES OF CONTENT TITLE PAGE i CERTIFICATION ii DEDICATION iii ACKNOWLEDGEMENT IV TABLES OF CONTENT V ABSTRACT VI CHAPTER ONE 1.0 INTRODUCTION 1.1 LITERATURE REVIEW 1.2 THE LIVER 1.2.1 CARBON TETRACHLORIDE 1.3.0 LIVER FUNCTION TEST 1.3.1 TOTAL CHOLESTEROL 1.3.6 FUNCTIONS OF THE LIVER 1.6.0 LIPID PEROXIDATION 1.8.2 BOTANICAL DESCRIPTION OF DENNETIA... Continue Reading

TITLE PAGE THE EFFECT OF HYDROALCOHOLIC EXTRACT OF AFRAMOMUM MELEGUETA ON SUPEROXIDE DISMUTASE ACTIVITY IN ALLOXAN INDUCED DIABETIC WISTAR ALBINO RATS BY EBELEME   EBENEZER NAU/ 2012474175 SUBMITTED TO THE DEPARTMENT OF APPLIED BIOCHEMISTRY FACULTY OF BIOSCIENCES IN PARTIAL FULFILMENT OF THE REQUIREMENTS FOR THE AWARD OF A BACHELOR OF SCIENCE... Continue Reading

A research on management of diabetes. ... Continue Reading

A research on management of diabetes. ... Continue Reading

ABSTRACT Cola nitida has been in use in the eastern parts of Nigeria for the management of certain ailments and as an aphrodisiac in the management of some sexual dysfunctions. However the effects of this extract in some health parameters in human objects have not been reported. This work, then, was aimed at investigating the effect of water... Continue Reading