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 Piliostigma reticulatum plant found in West Africa. It is an Evergreen shrub with a twisted bole to 9 m high, with a bushy spherical canopy. Bark dark grey to brown, fibrous and corky, slash dark red. Leaves large, thick, leathery, grey-green, 6-12 cm long, Fruit large, long, straight, undulate or twisted and hard, either glabrous or sparsely... Continue Reading

The purpose of this present study of seven Nigerian medicinal plants is to ascertain the medicinal, phytochemical and proximate constituents of the plants. The plants are .Acacia albida Del,   Anchomanes difformis Engl,   Boscia senegalensis,   Bridelia ferruginea Benth,  Ficus ingens (Miq.) Miq,  Indigofera arrecta   Hochst   and ... Continue Reading

The increasing incidence of resistance to antibiotics among bacteria currently poses serious clinical and public health threat and has propelled efforts for newer alternatives to alleviate the problem. Extensive search and testing for different plants with potentials for antimicrobial properties is presently considered one of the most feasible... Continue Reading

Spondias mombin is depends on for various herbal remedies for the treatment of numerous health conditions. This study  is to evaluate the In-vivo toxic effect of Stem bark extracts of Spondias mombin on in male and female albino rats. In-vivo   toxicity test was carried out with modified Lorke’s method. Forty two (42) male and female albino... Continue Reading

The seeds of a tropical fruit Carica papaya have been proven to have  anthelminthic activity. The main component in the seeds responsible for this  activity is Benzyl isothiocyanate. It is effective against parasites such Ascaris  lumbricoides, Strongyloides stercoralis, Taenia saginata and so on. The  research focus on formulating an... Continue Reading

Microsphere drug delivery systems are used to protect sensitive drugs from enzymatic degradation in the body, for controlled release and tissue targeting of the drug of interest. Starch and products derived from starch modification, are increasingly gaining acceptance in microsphere drug delivery. They are less expensive, non-toxic,... Continue Reading

    In the present study, optimized binary lipid matrices of Tallow fat- Transcutol and Precirol-Transcutol were used to formulate sustained release solid lipid nanoparticles loaded lumefantrine and ciprofloxacin. The homolipid (tallow fat from Bos indicus was extracted and purified following standard methods. Abinitio selection of lipid... Continue Reading

Starch is a naturally occurring polymer found in parts of the plants such as leaves, stems, tubers, and fruits. It is a commonly used excipient in pharmaceutical formulations because of its availability, affordability and inertness. Cyperus esculentus (tiger nut) is widely cultivated in the country especially in the northern part of... Continue Reading

  Globally, an estimated 3.4 billion people are at risk of malaria, including Nigerians. The current World Health Organization (WHO) Guideline for the treatment of malaria recommends the use of artemisinin combination therapy (ACT) for the treatment of uncomplicated malaria. Presently, the available formulations of ACTs are administered... Continue Reading

T he present study investigated herb-drug interactions involving cold water extract of Azadirachta indica (neem) leaves, with five classes of antibiotics, namely: Tetracyclines - Tetracycline (TET) and Doxycycline POX); I Penicillins - Penicillin G(PG) and Ampicillin (AMP); Cephalosporins - Cefuroxime (CF); Arninoglycosides -Gentamicycin... Continue Reading

The oral route is generally preferred for drug administration because of its ease and good patient compliance. In the search for new drugs for oral administration a major problem encountered is obtaining drug structures which, as well as being potent in viiro, possess favourable pharmacokinetic profiles which enable them to pass easily... Continue Reading

The study was aimed at evaluating the antidiabetic potentials of Anogeissius leiocarpus DC Guill and Perr root bark methanol, ethanol and ethanol plus trona extract; and preparing, characterizing and evaluating lipospheres as drug delivery system loaded with A.leiocarpus root bark methanol extract. 400 mg/kg of methanol,ethanol and... Continue Reading

Cyclophosphamide (CP) is one of the most potent and widely used alkylating anticancer agents. Urotoxicity and myelosuppression is known as the most prevailing dose-limiting toxicity associated with CP. In the present study, the protective potential of Vernonia amygdalina and Ocimum gratissimum aqueous leaf extracts in CP-induced... Continue Reading

Background: Outcomes of surgical versus medical management of first trimester incomplete abortion are poorly documented in Uganda and it is important to guide clinical practice. Objectives: To compare the effectiveness, secondary outcomes and satisfaction level between surgical and medical management of first trimçster incomplete... Continue Reading

Adolescents are considered as a nutritionally vulnerable subgroup. A rapid growth rate combined with marginal nutrient intakes increases the risk of nutritional deficiencies in this population. Poor nutritional status in adolescence compounds the risk of adolescent pregnancy and it is an important determinant of health outcomes at a later... Continue Reading

CHAPTER  ONE INTRODUCTION Definition:    Protein hydrolysate could be defined as the end product of protein hydrolysis using chemical and enzymic methods. Protein hydrolysate have many uses in specialty foods such as non allergenic infant formular, diets foods and other special nutritional foods. The drawback of many hydrolysates such as Soya... Continue Reading

nutritional benefit of iru on blood pressure control... Continue Reading

12 The  food  potentials  of  tigernut  tubers  (Cyperus  esculentus)  locally  know  as  “aki  awusa”  in Igbo,  ”aya”  in  Hausa  and  “ofio”  in  Yoruba  were  evaluated.  The  proximate  composition  of 100g  of  raw  and  processed  tigernuts  showed  that  moisture  content  of... Continue Reading

1.0 INTRODUCTION Fruit is a structural part of plant that contain seeds, normally fleshly, sweet and edible in a raw states, which includes; oranges, grapes, strawberries, juniper berries, pineapple and watermelon e.t.c (Abano, 2010). They are ripe ovaries or carpets that contain seed (McGee, 2004). Fruit contain various phytochemical compounds... Continue Reading

A nutrient is a substance used by an organism to survive, grow, and reproduce. The requirement for dietary nutrient intake applies to animals , plants , fungi , and protists. Nutrients can be incorporated into cells for metabolic purposes or excreted by cells to create non-cellular structures, such as hair, scales, feathers , or... Continue Reading

A few centuries ago, one might not have needed to keep fit or eat healthily. Today a lot of diseases and sickness are rampant due to obesity, malnutrition and not eating a balanced diet meal. In the 21st century, information is moving at the speed of light and people need to gain... Continue Reading

In recent years, there has been profound interest in the role of oxidative stress in the precipitation of pre- diabetic condition (1) and there are reports of oxidative stress increasing in patients with diabetes mellitus (2). Oxidative stress results when reactive forms of oxygen are produced faster than they can be safely neutralized by the body... Continue Reading

The study was carried out using randomized 121 in-patient diabetics in medical wards of University of Nigeria Teaching Hospital (UNTH) Ituku-Ozalla. The instrument for data collection was structured, validated pre-tested questionnaires, anthropometry and dietary study. Body mass index was calculated for each patient using weight and... Continue Reading

  This epidemiological study was to elicit information on the consumption pattern of antioxidant-rich foods among middle-aged adults in Enugu North local government area, Enugu State, Nigeria. Four hundred adult men and women aged 40-60 years were used for the study. Multiple- staged stratified random sampling technique was used for the... Continue Reading

This study was designed to assess the knowledge, attitude and adoption of appropriate infant feeding practices of mothers and the anthropometric indices of their children. Three hundred and seventy three mothers who attended infant welfare clinics at the three health settings (General hospital Ekwulobia, Primary health care Ekwulobia, and... Continue Reading