- Page 375

The presence study aimed to investigate the phytochemical and heavy metals level in selected vegetables grown in Kalambaina area ,the phytochemical were determined using analytical methods and the heavy metals (Cd, Pb, Zn, Ni, Cr and Cu) concentration in vegetables and water were determined using atomic absorption spectroscopy (AAS). The study... Continue Reading

Plants have long been a source of nutrition and therapy to man. The medicinal value of these plants lies in some chemical substances that produce a definite physiological action in the human body. This study evaluated the oxytocic potential of methanol extract of Sida acuta on female albino rats in vitro. Oxytocin was used as a standard... Continue Reading

Malaria is a significant public health problem in the world especially in in sub-Saharan Africa. One of the key contributory factors to the development and progression of malaria and its complications is oxidative stress, a condition characterized by increased production of free radicals or impaired antioxidant defence system.... Continue Reading

This research was conducted to determine the concentrations of heavy metals and proximate composition of different cereals (maize, millet and rice). Two different samples each sold in two different markets (Ogbete and Gariki) in Enugu, were used for this work, using atomic, absorption spectrophotometer. The heavy metal screening of the... Continue Reading

Diabetic mellitus is a metabolic disorder resulting from a defect in insulin secretion , insulin action or both . The deficiency of insulin leads to chronic hyperglycemia with disturbances of carbohydrate , fats   and protein metabolism . Kigelia Africana is a sausage tree known to have medicinal values. The aim of this work is to... Continue Reading

Several plants have been used in the treatment of various disorders without scientific basis. The present study examine the pancreatic effect of Buchholzia coriacea formulated diet in sucrose-fed pregnant rats and their offspring. Buchholzia coriacea seeds were obtained from Ogbete main market, Enugu state, identified, dried and grounded... Continue Reading

African trypanosomosis is a vector-borne disease that is caused by a flagellated protozoon of the genus Trypanosoma. Large populations of human and domestic animals are at risk of infections with trypanosomes in vast areas of sub-Saharan Africa where the disease is endemic. Human infections with trypanosomes are referred to as Human African... Continue Reading

Glutathione Peroxidase (GPx) family of enzymes plays important roles in the protection of organisms from oxidative damage. GPx converts reduced glutathione (GSH) to oxidized glutathione (GSSG) while reducing lipid hydroperoxides to their corresponding alcohols or free hydrogen peroxide to water. This study was conducted to investigate the possible... Continue Reading

    In this study, we evaluated the effect of the total phenol extract of Zanthoxylum zanthoxyloides leaves on oral glucose tolerance, lipid profile, liver function, oxidative stress parameters, and pancreas histopathology in diabetic rats. Diabetes was induced in rats by administration of alloxan monohydrate in a dose of 130 mg/kg b/w.... Continue Reading

Thonningia sanguinea is one of the herbal preparations vised prophylactieally against asthma at the Centre for Scientific Research into Plant Medicine. Preparations of this plant are used with Desmodium adseendens which has been shown to be anti-anaphylactic. The anaphylactic reaction is a basic underlying phenomenon in asthma. In this... Continue Reading

The toxicities of single antibiotics: ciprofloxacin, azithromycin, sulfathiazole and amoxicillin and their quaternary mixtures in different ratios were examined on three organisms Staphylococcus aureus, Bacillus cereus and Micrococcus luteus all isolated from Nworie River from three different points including the point of effluent... Continue Reading

Type 2 diabetes mellitus (T2DM) is a chronic progressive disease that has continued to be a global heath and economic burden. Acarbose is an antidiabetic drug, which acts by inhibiting alpha amylase and alpha glucosidase; while gallic acid is a simple phenolic acid that is widespread in plant foods and beverages such as tea and wine.This... Continue Reading

Adansonia digitata has popular ethnomedicinal application in the treatment of malaria in sub-Saharan Africa. The present study sought to investigate the antimalarial and antioxidant effects of methanol and flavonoid-rich extracts of the stem bark on Plasmodium berghei-infected mice in vivo. Thirty-five male mice, weighing 18-20 g and... Continue Reading

Human systemic fungal infections have increased in the past decade due to the dramatic increase in immunocompromised patients hence the emergence of resistant fungal strains. It is therefore necessary to discover new antifungal compounds with novel mode of action. This study was aimed at isolating and characterizing antifungal agents from... Continue Reading

Current efforts to eliminate malaria worldwide are soaring and one of the approaches to this is the mass screening of medicinal plants for their possible potential anti-malarial property. The current study conducted was to determine the effect of one such plant, Cryptolepis sanguinolenta on gametocyte development. In vitro growth... Continue Reading

The suitability o f five Schistosoma genus-specific monoclonal antibodies (MoAbs) (Sh3/34.10, Sh3/38.2, Sh4/14.3, Sh5/32.30 and Sh5/34.10) in detecting schistosome antigens in infected human and cattle was evaluated. These antibodies were employed in various diagnostic assays to diagnose human and animal schistosomiasis. Extant MoAb... Continue Reading

This study assessed the phytochemical and nutrient compositions of edible yam species Dioscorea rotundata 1, Dioscorea rotundata 2, Dioscorea rotundata 3, Dioscuri rotundata 4, Dioscorea Cayenensis, Dioscorea alata, Dioscorea dumentorum and Dioscorea bulbifera in Southeastern Nigeria. The phytochemical and nutrient (proximate, minerals,... Continue Reading

Among medicinal plants, Picralima nitida is well investigated and has been shown to possess renal and hepatoprotective activities. The present study was conducted to investigate the chemoprotective effect of methanol extract of Picralima nitida leaves on carbon tetrachloride-induced oxidative stress in albino rats. Thirty (30) Wistar... Continue Reading

The impact of pollution due to gas flaring on individuals native to Ebocha in Niger Delta Area was investigated. One hundred and five apparently healthy individuals between 21-70years who consented for the study were screened, seventy five individuals from Ebocha and thirty from Nsukka-a control location with no history of petroleum... Continue Reading

The burden of hyperlipidemia is on the rise globally especially in many low income countries like Uganda. Management of this metabolic disorder mainly involves dietary and behavioral therapies, which are often met with poor results as they require time and discipline from the patients. The chemotherapeutic options available are expensive,... Continue Reading

The burden of hyperlipidemia is on the rise globally especially in many low income countries like Uganda. Management of this metabolic disorder mainly involves dietary and behavioral therapies, which are often met with poor results as they require time and discipline from the patients. The chemotherapeutic options available are expensive,... Continue Reading

We visited various locations during the time of our field exercise which include: Ekerekunta, Akpoha, Ogo ubi, Okpo ezi, Amaeta Enu. The present study area is bound within the latitude of 5055” N to 6° 0’ 0” N and longitude of 7055” E to 8° 1’ 0” E in the Southern Benue Trough within the Afikpo syncline and Abakaliki... Continue Reading

    The integrated study involving electrical resistivity method and physicochemical analysis of water samples was carried out to investigate the effect of dumpsite leachate on groundwater repositories around the dumpsites in Ikot Ekpene, Uyo and Eket Local Government Areas of Akwa Ibom State. A total of thirty-three (33) vertical... Continue Reading

DStv is the only provider of pay television in Zimbabwe at present with over 70 000 subscribers registered country wide. DStv is the flagship product of Multichoice providing various bouquets offering General Entertainment, Movies, Lifestyle & Culture, Sport, Documentaries, News and Commerce, Children, Music Religion and Consumer channels... Continue Reading

Road traffic injuries among motorcyclists worldwide have persisted as a serious public health problem with much of the health burden in the developing countries especially the middle and low-income countries. This problem has not excluded Ghana which continually suffers from road traffic injuries and fatalities mainly caused by over... Continue Reading