Recent Pharmaceutical Science Project Topics and Materials

PROPOSAL: ABSTRACT Background: Currently stroke represents a serious problem in public health as one of the leading causes of  mortality and morbidity worldwide [1-3] with developing countries accounting for 85% of global deaths from stroke  [1, 3-5]. A very good example explains how stroke seems to be increasing in Nigeria and the case fatality... Continue Reading

The use of herbal medicines, despite the advancement in production of orthodox ones, has been on the increase, both in underdeveloped, developed and developing countries like Nigeria in particular. The approval of these herbal remedies by regulatory bodies like the National Agency for Food and Drug Administration Control, (NAFDAC) in Nigeria has... Continue Reading

The field of nano science plays a crucial role in modern research and technology, offering unparalleled opportunities for innovation. Spondias mombin extract is used in this study as a bioreducing agent for the biosynthesis of silver nanoparticles (AgNPs). The properties of these nanoparticles are compared. As the color of the extract changed from... Continue Reading

ABSTRACT  Fatty seed extracts of Vitellaria paradoxa (Sapotaceae), an indigenous plant of West Africa is a popular remedy for arthritis and swellings. This study investigated the knowledge, prevalence and pattern of use of the fatty extract also known as shea butter in clinically diagnosed arthritic patients as well as its effects on acute... Continue Reading

ABSTRACT The usefulness of non-steroidal anti-inflammatory agents in the management of rheumatoid diseases cannot be over-emphasized. As this disease is characterized by chronic inflammation, it is usual to test compounds for anti-inflammatory activity in animals and then hope that the active ones should be clinically useful as anti-rheumatic... Continue Reading

ABSTRACT Globally, an estimated 3.4 billion people are at risk of malaria, including Nigerians. The current World Health Organization (WHO) Guideline for the treatment of malaria recommends the use of artemisinin combination therapy (ACT) for the treatment of uncomplicated malaria. Presently, the available formulations of ACTs are administered... Continue Reading

ABSTRACT Hawked foods are cheap and easily accessible and have met the food needs of people in many cities and towns of developing countries. This study was aimed at ascertaining the diversity of microbial contaminants in foods hawked in Nsukka town. Seven different food samples of cooked foods hawked in Nsukka were examined for the presence of... Continue Reading

ABSTRACT The aqueous methanolic extracts of 20 selected plant parts were screened for in-vitro antimicrobial activity against clinical strains of Staphylococcus aureus, Bacillus subtilis, Klebsiella pneumonia, Salmonella typhi, Escherichia coli, Pseudomonas aeruginosa, Aspergillus niger and Candida albicans at a test concentration of 10mg/ml using... Continue Reading

CONTENTS Page Acknowledgement ........................................................................................................... iv Abstract ................................................................................................................................. vi List of Tables... Continue Reading

ABSTRACT The anxiolytic and antinociceptive properties of the leaf extract and fraction of Phyllanthus muellerianus Kuntze (Phyllanthaceae) were investigated.The extract (MME; 500.18 g; 10%w/w), obtained by cold maceration in 1:1 mixture of methylene chloride: methanol for 48 h, was fractionationed in a silica gel column which yielded the ethyl... Continue Reading

This research project studied the effect of ethanolic leaf extract of Dialium guineense Willd (Fabaceae) on oral glucose tolerance in mice and alloxan-induced diabetic female rats.  The ethanolic leaf extract was prepared by marcerating 500g of the dried, milled leaves of D. guineense in 3L of 96% ethanol in a suitable sized plastic bucket/bowl... Continue Reading

ABSTRACT The objective of this research was to investigate the anti-hyperglyceamic properties of the aqueous extract green peel of (Banana) musa acuminata 'nakitembe cultivar' in alloxan induced diabetic rats. The extract used was obtaned from the green banana dried and phytochemical analysis and acute toxicity study carried out. Alloxan was... Continue Reading

ABSTRACT  Introduction: It has been reported that the main factors behind the emergence of drug resistance is the use and misuse of antimicrobial drugs during the past few decades, but there is also the aspect of epidemic spread of drug-resistant bacteria as a factor. This has caused a major concern with serious implications in human and animal... Continue Reading

ABSTRACT.  Prevention of irrational use of medicines may reduce healthcare costs and potentially save I ives. In line with World Health Organization (WHO) recommendation, a retrospective, cross-sectional descriptive study was carried out to obtain information on prescribing in the general outpatient department of Kampala International University... Continue Reading

ABSTRACT The indiscriminate use of antibiotics has become a global problem with implications for effective therapy of infections and dose resistance. The objective of this study is to determine the profile of antibiotic use at the Regional Hospital Buea. The data used for this study was obtained using a Checklist and the data obtained were... Continue Reading

ABSTRACT Erlangea tomentosa is been used traditionally in the management of several diseases including pain and inflammation. However, their efficacy has not been scientifically validated. The aim of this study therefore is to investigate the analgesic and anti-inflammatory activities of the aqueous leaf extract. The plant materials were collected... Continue Reading

The study was conducted to evaluate the efficacy of tiptop yogurt as a some of probiotics against enteric pathogens isolated at KIU-TH. It was conducted to isolate and identify any probiotics available in yogurt, obtain cell free supernatants (bacteriocins) and expose them to 0 selected enteric pathogens, evaluate the effect of bacteriocins from... Continue Reading

TABLE OF CONTENTS DECLARATION .................................................................................................................................. i CERTIFICATION ............................................................................................................................... ii DEDICATION... Continue Reading

TABLE OF CONTENTS DECLARATION ........................................................................................................................................................ 1 APPROVAL... Continue Reading

TABLE OF CONTENTS DECLARATION ............................................................................................................................... i ACKNOWLEDGEMENT ................................................................................................................ ii DEDICATION... Continue Reading

TABLE OF CONTENTS DECLARATION .......................................................................................................................................... ii DDEDICATION ............................................................................................................................................. iii ACKNOWLEDGEMENT... Continue Reading

Table of Contents Declarations •...••.•...•....•...•.••••.•••••.•.•.•.•••.•.•..•.•..........•.•.....................................................................•.•.....•...•• i Approval... Continue Reading

TABLE OF CONTENTS DECLARATION ............................................................................................................................. .i CERTIFICATION .......................................................................................................................... ii LIST OF ABREVIATIONS... Continue Reading

ABSTRACT Hepatotoxicity and oxidative stress are some of the molecular mechanism of Dichlorvos toxicity. This study aims at dertermining the antipoisoning and protective properties of Elaeis oleifera palm oil extract in orally dichlorvos poisoned albino rats. 35 rats were divided into seven groups each containig five rats served as subject for... Continue Reading

TABLE OF CONTENTS CONTENT PAGE Title ............................................................................................................................................ . Declaration .................................................................................................................................. i Dedication... Continue Reading