+234 813 0686 500
+234 809 3423 853
info@grossarchive.com

In vitro ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL PROPERTIES OF METHANOL, ETHANOL AND HEXANE EXTRACTS OF Azadirachta indica LEAVES.

  • Type:Project
  • Pages:81
  • Format:Microsoft Word
(Bio-Chemistry Project Topics & Materials)

ABSTRACT

Azadirachta indica, commonly known as Neem, has attracted worldwide prominence in recent years as a cynosure of modern medicine owing to its wide range of medicinal properties. This study was carried out to investigate the phytochemical properties and antioxidant activity of the multi-solvent (methanol, ethanol and hexane) extracts of the leaves of Azadirachta indica of Meliaceae family. The extracts were investigated for phytochemical constituents such as tannins, saponins, alkaloids, total flavonoids, total phenols and proanthocyanidin, while the in vitro antioxidant activity was determined using DPPH scavenging assay, FRAP assay, metal ion chelating assay and reducing power assays. Total phenol content of extracts were also determined by Folin-Ciocalteu method. Experimental results obtained for phytochemical studies revealed that flavonoids content is highest in the methanol extract (79.10±1.15 mg QE/g extract), while the ethanol extract had the lowest content. Also, the methanol extract of A. indica leaves has the highest fraction of crude extract, highest phenol content (342±10.2 mg GAE/g extract), highest tannin content (97.83±3.49 mg TAE/g extract), highest proanthocyanidin content (13.17±2.85 mg AAE/g extract). Qualitative studies show the presence of the various phytochemicals in varying amounts; however, cardiac glycosides were absent in the hexane and ethanol extracts, alkaloids were absent in the ethanol extract, while saponins were absent in the hexane extract. Similarly, IC50 values of the ethanolic extract of A. indica leaves (IC50 values of 81.62µg/ml and 83.29µg/ml) were lower than other extracts for DPPH scavenging assay and metal ion chelating respectively. The various extracts of A. indica leaves may be exploited for clinical medicine as potent factors because of their high antioxidant activity.

In vitro ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL PROPERTIES OF METHANOL, ETHANOL AND HEXANE EXTRACTS OF Azadirachta indica LEAVES.

Share This

Details

Type Project
Department Bio-Chemistry
Project ID BCH0161
Price ₦3,000 ($9)
No of Pages 81 Pages
Format Microsoft Word

500
Leave a comment...

    Details

    Type Project
    Department Bio-Chemistry
    Project ID BCH0161
    Price ₦3,000 ($9)
    No of Pages 81 Pages
    Format Microsoft Word

    Related Works

    ABSTRACT Azadirachta indica, commonly known as Neem, has attracted worldwide prominence in recent years as a cynosure of modern medicine owing to its wide range of medicinal properties. This study was carried out to investigate the phytochemical properties and antioxidant activity of the multi-solvent (methanol, ethanol and hexane) extracts of the... Continue Reading
    ABSTRACT Comparative assessment of the phytochemical content and antioxidant potential of Azadirachta indica (neem) and Parquetina nigrescens (bullock) is the aim of this study. In order to achieve this, both plants were harvested from the botanical garden, University of Ibadan. The leaves were removed from the stem, washed with running water to... Continue Reading
    ABSTRACT This study focused on the comparative study of the phytochemical constituents, in vitro antioxidant activity of the stem bark and seed oil extracts of Allanblackia floribunda. The phytochemical screening revealed that both extracts contain flavonoids, tannins, cardiac glycosides, alkaloids and saponins while terpenoids are absent in the... Continue Reading
    ABSTRACT This study focused on the comparative study of the phytochemical constituents, in vitro antioxidant activity of the stem bark and seed oil extracts of Allanblackia floribunda. The phytochemical screening revealed that both extracts contain flavonoids, tannins, cardiac glycosides, alkaloids and saponins while terpenoids are absent in the... Continue Reading
    ABSTRACT Twenty-two healthy albino mice were grouped into A, B, C, D, and E. Group A had six mice while groups B – E had four mice each. The mice were infected with Plasmodium berghei and the methanol extract of the leaves of Adansonia digitata was obtained by maceration extraction method. Phytochemical screening of the plant extract revealed... Continue Reading
    ABSTRACT The global scenario is now supporting the development of modern drugs from less toxic plant products with proven medicinal properties. Each part of the neem plant (Azadirachta indica A. Juss) reportedly has various medicinal properties and has been in use in many continents for... Continue Reading
    ABSTRACT The global scenario is now supporting the development of modern drugs from less toxic plant products with proven medicinal properties. Each part of the neem plant (Azadirachta indica A. Juss) reportedly has various medicinal properties and has been in use in many continents for centuries. In this project work, water extract from Neem... Continue Reading
    ABSTRACT Adansonia digitata L. (Malvaceae) is commonly known as baobab tree native to Africa. Baobab is a multi-purpose tree which offers protection and provides food, clothing and medicine as well as raw material for many useful items. This study aims to elucidate the metal chelating and ferric reducing potentials of methanol extracts of... Continue Reading
    ABSTRACT Studies were conducted to determine the phytochemicasl present in moringa olrifera and Azadrichta indica leaves. Leaves for this work were washed, room dried ground to powder. The ground leave for both sample were soaked in four different solvent; Ethanol, n-Hexane,... Continue Reading
    PHYTOCHEMICAL ANALYSIS ON MORINGA OLEIFERA AND AZADRICHTA INDICA LEAVES ABSTRACT Studies were conducted to determine the phytochemicasl present in moringa olrifera and Azadrichta indica leaves. Leaves for this work were washed, room dried ground to powder. The ground leave for both sample were soaked in four different solvent; Ethanol, n-Hexane,... Continue Reading