The purpose of this study was to investigate the influence of female head teachers’ leadership behaviour on teacher efficacy in selected public basic schools in Amansie west district of the Ashanti Region. The study used descriptive research design. Questionnaire that had closed-ended questions were used to obtain information for the study. The targeted population for this study comprised all the 17 female head teachers and 170 teachers who have females as their heads in the public basic schools in Amansie West District. Census sampling was used to select all the 187 female head teachers and teachers for the study. The analytical procedure used was descriptive statistics. Among the major findings were that head teachers’ leadership behaviour strategies were delegating responsibilities to other teachers when necessary and making sure that teachers follow laid down rules and regulations. Teacher selfefficacy strategies were teachers’ ability to control disruptive behaviour in the classroom and motivating students who show low interest in school work. Leadership behaviour of head teachers impacted on teacher efficacy as they create supportive environment that promote teachers to maximize their potential to be able to teach to the understanding of students and also create a productive atmosphere for teaching and learning. It is recommended based on the findings that the Ghana Education Service (GES) through the Metropolitan, Municipal and District Directors should organize training workshops on effective leadership style for female head teachers.